A case report of hydatidiform mole:A Diagnostic Dilemma

Malini Bharadwaj; Tarani Shinde

doi:10.17511/joog.2019.i01.05

Dr. Malini Bharadwaj Professor & Head, Department of Obstetrics & Gynecology, J.K. Hospital & L.N. Medical College, Bhopal, MP, India
Dr. Tarani Shinde Resident, Department of Obstetrics & Gynecology, J.K. Hospital & L.N. Medical College, Bhopal, MP, India

DOI: https://doi.org/10.17511/joog.2019.i01.05

Keywords: Molar pregnancy, Gestational trophoblastic disease, Hyperthyroidism, Hydatidiform mole

Abstract

Molar pregnancy is a part of gestational trophoblastic disease, and can rarely be associated with hyperthyroidism. We report a case of complete hydatidiform mole who initially presented as one and half month amenorrhea and bleeding per vaginum, with an ultrasonography report suggestive of multiple gestational sacs without any fetal pole, leading to a provisional diagnosis of threatened abortion. Then, routine investigations were done and raised beta HCG value were suggestive of choriocarcinoma and hydatidiform mole which was later confirmed by histopathological examination.

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References

1. Seckl MJ, Gillmore R, Foskett M, et al. Routine terminations of pregnancy--should we screen for gestational trophoblastic neoplasia? Lancet. 2004 Aug 21-27;364(9435):705-7.DOI:10.1016/S0140-6736(04)16898-0.

2. Brown J, Naumann RW, Seckl MJ, et al. 15years of progress in gestational trophoblastic disease: Scoring, standardization, and salvage. Gynecol Oncol. 2017 Jan;144(1):200-207. doi: 10.1016/j.ygyno.2016.08.330. Epub 2016 Oct 13.

3. Berek&NovaksGynaecology 15th edition, p. 2537-2542.

4. Santaballa A, García Y, Herrero A, et al. SEOM clinical guidelines in gestational trophoblastic disease (2017). Clin Transl Oncol. 2018 Jan;20(1):38-46. doi: 10.1007/s12094-017-1793-0. Epub 2017 Nov 17.[pubmed]

5. Bhat, S., Maletkovic, J. A Hydatidiform Mole Can Cause Severe Gestational Hyperthyroidism. Clin Thyroidol 2013; 25:298-300.

6. Fukunaga M, Katabuchi H, Nagasaka T, Mikami Y, Minamiguchi S, Lage JM. Interobserver and intraobserver variability in the diagnosis of hydatidiform mole. The American journal of surgical pathology. 2005 Jul 1;29(7):942-7.

7. Lage JM, Popek EJ. The role of DNA flow cytometry in evaluation of partial and complete hydatidiform moles and hydropic abortions. In Seminars in diagnostic pathology 1993 Aug (Vol. 10, No. 3, pp. 267-274).

8. Lage JM. Diagnostic dilemmas in gynecologic and obstetric pathology. Semin Diagn Pathol. 1990 May;7(2):146-55.[pubmed]

9. Conran RM, Hitchcock CL, Popek EJ, Norris HJ, Griffin JL, Geissel A, McCarthy WF. Diagnostic considerations in molar gestations. Human pathology. 1993 Jan 1;24(1):41-8.[pubmed]

10. Howat AJ, Beck S, Fox H, Harris SC, Hill AS, Nicholson CM, Williams RA. Can histopathologists reliably diagnose molar pregnancy?. Journal of clinical pathology. 1993 Jul 1;46(7):599-602.

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