Case report of primary serous adenocarcinoma of fallopian tube - a diagnostic dilemma

  • Dr. Susheela Gayam Department of Obstetrics and Gynaecology, Vijay Marie Hospital, Hyderabad, India
  • Dr. Chinna Babu Dept of Surgical Oncology, Apollo Hospital, Hyderabad, India
  • Dr. Lakshmi V.V.S Department of Obstetrics and Gynaecology, Vijay Marie Hospital, Hyderabad, India
  • Dr. Srinivas Maddali Histopathology & Cytology Laboratory, Hyderabad, India
Keywords: Primary fallopian tube neoplasm, Intra-operative Evaluation, Surgical Procedure, Histopathological Diagnosis, Serous Adenocarcinoma, Staging, Chemotherapy

Abstract

Historically, primary fallopian tube carcinoma constitutes 0.3% of all cancers of the female genital tract. But literature suggests that the primary fallopian tube carcinoma may be more common. The true incidence of fallopian tube cancer may be underestimated because of the convention of assigning many of these as ovarian cancer when the site of origin is unclear. The preoperative diagnosis is difficult due to the lack of specific symptoms. Fallopian tube carcinoma clinically behaves like epithelial ovarian cancer and histologically similar to it; thus, the evaluation and treatment are essentially the same. We report here a typical case of primary fallopian tube cancer in a 48 year old female diagnosed as ovarian tumour, preoperatively by radiological imaging but was recognized as fallopian tube carcinoma intraoperatively and was confirmed by histopathology.

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References

1. Kalampokas E, Kalampokas T, Tourountous I. Primary fallopian tube carcinoma. Eur J Obstet Gynecol Reprod Biol. 2013 Jul;169(2):155-61. doi: 10.1016/j.ejogrb.2013.03.023. Epub 2013 Apr 23.[pubmed]

2. Lau HY, Chen YJ, Yen MS, et al. Primary fallopian tube carcinoma: a clinicopathologic analysis and literature review. J Chin Med Assoc. 2013;76(10):583–7. https://doi.org/10.1016/j.jcma.2013.06.010 .

3. Mladenovic-Segedi L. Primary fallopian tube carcinoma. Med Pregled. 2009;62(1-2):31–6. https://doi.org/10.2298/MPNS0902031M . PMid: 19514598.

4. Howitt BE, Hanamornroongruang S, Lin DI, et al. Evidence for a dualistic model of high-grade serous carcinoma: BRCA mutation status, histology, and tubal intraepithelial carcinoma. Am J Surg Pathol. 2015 Mar;39(3):287-93. doi: 10.1097/PAS.0000000000000369.[pubmed]

5. Quartuccio SM, Karthikeyan S, Eddie SL, et al. Mutant p53 expression in fallopian tube epithelium drives cell migration. Int J Cancer. 2015 Oct 1;137(7):1528-38. doi: 10.1002/ijc.29528. Epub 2015 Apr 11.[pubmed]

6. Wang PH, Yuan CC, Chao HT, et al. Prognosis of primary fallopian tube adenocarcinoma: report of 25 patients. Eur J Gynaecol Oncol. 1998;19(6):571-4.[pubmed]

7. Rexhepi M, Trajkovska E, Ismaili H, Primary Fallopian Tube Carcinoma: A Case Report and Literature Review. Open Access Maced J Med Sci. 2017 May 20;5(3):344-348. doi: 10.3889/oamjms.2017.044. eCollection 2017 Jun 15.[pubmed]

8. Nordin AJ. Primary carcinoma of the fallopian tube: a 20-year literature review. Obstet Gynecol Surv. 1994 May;49(5):349-61.[pubmed]

9. Kalyani R, Kumar ML, Srikantia SH. et al. Primary adenocarcinoma of fallopian tube--a case report. Indian J Pathol Microbiol. 2005 Apr;48(2):219-21.[pubmed]

10. Koo Yu-Jin K, Kyoung-Shil I, Yong-Soon K. Primary fallopian tube carcinoma: a clinicopathological analysis of a rare entity. International Journal of Clinical Oncology. 2011;16(1):45–49. https://doi.org/10.1007/s10147-010-0128-8 .

11. Huber-Buchholz MM, Buchholz NP, Staehelin J. Analysis of 23 cases of primary carcinoma of the fallopian tube over 50 years. J Obstet Gynaecol Res. 1996 Jun;22(3):193-9.[pubmed]

12. Horng HC, Teng SW, Huang BS, et al. Primary fallopian tube cancer: domestic data and up-to-date review. Taiwan J Obstet Gynecol. 2014 Sep;53(3):287-92. doi: 10.1016/j.tjog.2014.07.003.[pubmed]

13. Chaudhry S, Hussain R, Zuberi MM, et al. Rare primary fallopian tube carcinoma; a gynaecologist's dilemma. J Pak Med Assoc. 2016 Jan;66(1):107-10.[pubmed]

14. Berek JS, Crum C, Friedlander M. Cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet. 2015 Oct;131 Suppl 2:S111-22. doi: 10.1016/j.ijgo.2015.06.007.[pubmed]

15. Gomes FV, Dias JL, Lucas R, Cunha TM. Primary fallopian tube carcinoma: review of MR imaging findings. Insights Imaging. 2015;6:431–439. https://doi.org/10.1007/s13244-015-0416-y.

16. Hariprasad P, S H, Srinivas T, et al. Primary bilateral fallopian tube carcinoma the report of a single case with review of the literature. J Clin Diagn Res. 2013 May;7(5):930-2. doi: 10.7860/JCDR/2013/5483.2980. Epub 2013 Mar 7.
Case report of primary serous adenocarcinoma of fallopian tube - a diagnostic dilemma
CITATION
DOI: 10.17511/joog.2018.i04.01
Published: 2018-12-31
How to Cite
Gayam, S., Babu, C., V.V.S, L., & Maddali, S. (2018). Case report of primary serous adenocarcinoma of fallopian tube - a diagnostic dilemma. Obs Gyne Review: Journal of Obstetric and Gynecology, 4(4), 73-76. https://doi.org/10.17511/joog.2018.i04.01
Section
Case Report