Assessment of serum Lactate Dehydrogenase in preeclamptic pregnant women

  • Dr. Radha Nair Associate Professor, Department of OBG, Al Azhar Medical College and Super speciality Hospital, Thodupuzha ,Idukki (DT), Kerala, India
  • Dr. Vilasiny Narayanan Narayanan, Assistant Professor, Department of OBG, Kerala Medical College and Hospital, Palakkad, Kerala, India
Keywords: Preeclampsia, LDH, Third trimester

Abstract

Background: Evidences prove that endothelial cell and altered endothelial cell function play an important role in the pathogenesis of preeclampsia. Therefore serum lactate dehydrogenase (LDH) is useful biochemical markers reflecting the severity of the occurrence of preeclampsia.

Objective: Determination of serum lactate dehydrogenase (LDH) in severe preeclamptic pregnant women.

Methods: This is the case-control hospital based study carried in the Al Azhar Medical College and Super speciality Hospital, Thodupuzha. Normal pregnant women (n=55) and women with severe preeclampsia (n=63) were included in the study. Both the groups were in their third trimester and of same age and same gestational age. Serum LDH levels were measured by continuous spectrophotometric pyruvate method for both groups.

Results: Higher values of serum lactate dehydrogenase (LDH) were found in severe preeclamptic women compared with normal pregnant women in third trimester.

Conclusion: Elevated levels of serum LDH indicates the tissue damage and might be the cause of the occurrence of preeclampsia.

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Assessment of serum Lactate Dehydrogenase in preeclamptic pregnant women
CITATION
DOI: 10.17511/joog.2016.i03.01
Published: 2019-09-30
How to Cite
Nair, R., & Narayanan, V. (2019). Assessment of serum Lactate Dehydrogenase in preeclamptic pregnant women. Obs Gyne Review: Journal of Obstetric and Gynecology, 2(3), 26-29. https://doi.org/10.17511/joog.2016.i03.01
Section
Original Article