Pregnancy in patients with thalassemia intermedia: A rare case report

Abstract

Background: Annual incidence of -thalassemia is 1/100,000 throughout world. Asian countries like India, Pakistan, and Bangladesh account for 79% thalassemia births. -thalassemia is inherited as an autosomal recessive disorder. It is most common single gene disorder, considered as most widespread genetic disease in the world. -thalassemia intermedia is the most common cause of chronic hemolytic anemia and accounts for one-fourth of -thalassemia cases.

Case Report: Here we report a case of 22 year old woman presented to ANC clinic at our hospital, referred from private in view of primigravida with 37+3 weeks of gestation with fetal growth restriction (FGR) with known case of hypothyroidism; there was history of splenectomy in childhood. Labor was induced in view of severe FGR and patient underwent cesarean section for non-progress of labor with fetal distress, delivered a male child of 1.6 kg. Her postoperative period was uneventful. She received thromboprophylaxis postoperatively and discharged in satisfactory condition. Patient was advised to review after 6 months for evaluation of baby in pediatric OPD. A multidisciplinary approach is required to manage these patients.

Conclusion: Multidisciplinary team approach is required for in pregnancy with thalassemia. Strict monitoring and early management of complications can lead to optimal fetomaternal outcomes.